解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Neospora caninum is a cyst-forming parasite that causes abortion in cattle. Despite this parasite's ubiquitous distribution and wide host range, the number of N. caninum isolates obtained to date is limited. In vitro isolation of the parasite is arduous and often unsuccessful. In addition, most isolates have been obta...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118200800509X
更新日期:2008-12-01 00:00:00
abstract::We conducted the first comprehensive study on the spatiotemporal structure of trematode communities in the large-mouthed valve snail, Valvata macrostoma. A total of 1103 snails were examined monthly between May and October 2007 from Lake Konnevesi, Central Finland, from a shallow (1-2 m deep) and an offshore site (5-6...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008005027
更新日期:2008-12-01 00:00:00
abstract::Planning of the control of Plasmodium falciparum malaria leads to a need for models of malaria epidemiology that provide realistic quantitative prediction of likely epidemiological outcomes of a wide range of control strategies. Predictions of the effects of control often ignore medium- and long-term dynamics. The com...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008000371
更新日期:2008-11-01 00:00:00
abstract::An M13 phage random 12-mers peptide library was used to screen cathepsin L mimotopes of Fasciola hepatica and to evaluate their immunogenicity in sheep. Seven clones showed positive reactivity to a rabbit anti-cathepsin L1/L2 antiserum in ELISA, and their amino acid sequences deduced by DNA sequencing were tentatively...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118200800471X
更新日期:2008-10-01 00:00:00
abstract::We cloned and expressed Echinostoma caproni HSP70 in Escherichia coli. This molecule presents an open reading frame (ORF) of 655 amino acids, and a theoretical molecular weight of 71 kDa. E. caproni HSP70 protein showed a high homology to other helminth molecules, major differences being located in the C-terminal regi...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004927
更新日期:2008-10-01 00:00:00
abstract::Oesophagostomum dentatum stages were investigated for glutathione S-transferase (GST) expression at the protein and mRNA levels. GST activity was detected in all stages (infectious and parasitic stages including third- and fourth-stage larvae of different ages as well as males and females) and could be dose-dependentl...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004769
更新日期:2008-09-01 00:00:00
abstract::The effect of sainfoin (Onobrychis viciifolia) hay consumption on the pathophysiology and local cellular responses of growing lambs during infection with Trichostrongylus colubriformis was investigated. Thirty-two lambs, 16 weeks of age, were allocated to 1 of 4 treatment groups (n=8) that were offered either grass (G...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004563
更新日期:2008-08-01 00:00:00
abstract::In previous studies, ultrastructural observations revealed a large number of gap junctions (GJs) in the neck and immature proglottid tissues of Taenia solium tapeworms. In these helminths, cytoplasmic glycogen sacs are connected by numerous discrete GJs to other cells throughout the maturing strobilar tissue. Disconti...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004629
更新日期:2008-08-01 00:00:00
abstract::The relative importance of temporal and spatial effects was assessed in helminth communities of bank voles (Myodes glareolus) in 3 woodland sites in N.E. Poland in the late summers of 1999 and 2002. Among common species the rank order of sites in relation to prevalence and abundance of infection was maintained between...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004484
更新日期:2008-07-01 00:00:00
abstract::Infection of small macropodids with the larval stage of Echinococcus granulosus can cause fatalities as well as significant pulmonary impairment and other adverse sequelae. The brush-tailed rock-wallaby (Petrogale penicillata) is a small macropodid listed as vulnerable on the IUCN's Red List of Threatened Species. Thi...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004423
更新日期:2008-05-01 00:00:00
abstract::Ligand-gated chloride channels (LGCCs) are key components of the nervous system of parasitic nematodes and important targets for anthelmintics. Here, we describe the isolation and characterization of a novel member of the LGCC gene family (HcLGCC1) from the parasitic nematode Haemonchus contortus. Sequence analysis re...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007004088
更新日期:2008-04-01 00:00:00
abstract::Blood examination by microhaematocrit and haemoculture of 459 snakes belonging to 37 species revealed 2.4% trypanosome prevalence in species of Viperidae (Crotalus durissus and Bothrops jararaca) and Colubridae (Pseudoboa nigra). Trypanosome cultures from C. durissus and P. nigra were behaviourally and morphologically...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004253
更新日期:2008-04-01 00:00:00
abstract::Given the worldwide decline of amphibian populations due to emerging infectious diseases, it is imperative that we identify and address the causative agents. Many of the pathogens recently implicated in amphibian mortality and morbidity have been fungal or members of a poorly understood group of fungus-like protists, ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007003708
更新日期:2008-02-01 00:00:00
abstract::A study carried out on a sheep farm examined whether Toxoplasma gondii foetal infection and associated abortion occur in successive lambings. We identified 29 ewes that gave birth to lambs on at least 2 successive years over our study period, 2000-2003. Tissue samples from the progeny of these ewes were analysed by PC...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007003721
更新日期:2008-02-01 00:00:00
abstract::Balb/c mice infected with the gastrointestinal nematode Heligmosomoides bakeri were fed protein sufficient (PS, 24%) or deficient (PD, 3%) diets to investigate whether diet, infection or dose of larval challenge (0, 100 or 200 larvae) influenced gut pathophysiology and inflammation. Among the PS mice, worms were more ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007003617
更新日期:2008-01-01 00:00:00
abstract::We have recently identified 2 surface proteins in Entamoeba histolytica as intermediate subunits of galactose- and N-acetyl-D-galactosamine-inhibitable lectin (EhIgl1 and EhIgl2); these proteins both contain multiple CXXC motifs. Here, we report the molecular characterization of the corresponding proteins in Entamoeba...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007003459
更新日期:2007-12-01 00:00:00
abstract::Neospora caninum causes economical impact in cattle-raising farms since it is implicated as the major cause of bovine abortions. Although infection by the parasite has been widely described in mammals, the role of birds in its life-cycle is still obscure. Therefore, this work aimed to evaluate the infection by N. cani...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007003344
更新日期:2007-12-01 00:00:00
abstract::Expansion of human activities frequently results in habitat fragmentation, a phenomenon that has been widely recognized in the last decades as one of the major threats to world's biodiversity. The transformation of a continuous forest into a fragmented area results in a hyper-dynamic landscape with unpredictable conse...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118200700323X
更新日期:2007-11-01 00:00:00
abstract::The current trend of antimony (Sb) unresponsiveness in the Indian subcontinent is a major impediment to effective chemotherapy of visceral leishmaniasis (VL). Although contributory mechanisms studied in laboratory-raised Sb-R parasites include an up-regulation of drug efflux pumps and increased thiols, their role in c...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007003150
更新日期:2007-11-01 00:00:00
abstract::In this review, we envisage the host environment, not as a hostile one, since the schistosome thrives there, but as one in which the relationship between the two organisms consists of constant communication, through signalling mechanisms involving sense organs, surface glycocalyx, surface membrane and internal organs ...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182007002971
更新日期:2007-10-01 00:00:00
abstract::Within the genus Cryptosporidium 2 lineages have evolved, one adapted to the acid environment of the stomach and abomasum, the other comprising parasites that multiply in the small intestine. We tested whether the release of sporozoites from oocysts, a process known as excystation, is triggered by conditions which mim...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007002922
更新日期:2007-10-01 00:00:00
abstract::Leishmania donovani causes visceral disease (kala-azar), a major health problem throughout the tropics with 500 000 new cases every year. Leishmania differentiates from the promastigote to the amastigote form to establish infection in a mammalian host. To understand the process of differentiation, we assessed the glob...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118200700296X
更新日期:2007-10-01 00:00:00
abstract::Cercariae of the bird schistosome Trichobilharzia regenti and of the human schistosome Schistosoma mansoni employ proteases to invade the skin of their definitive hosts. To investigate whether a similar proteolytic mechanism is used by both species, cercarial extracts of T. regenti and S. mansoni were biochemically ch...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007002910
更新日期:2007-10-01 00:00:00
abstract::Leishmania produce several types of mucin-like glycoproteins called proteophosphoglycans (PPGs) some of which are secreted while others are found on the surface of promastigotes and amastigotes. These proteins are thought to be important in the transmission, invasion and subsequent intracellular survival of parasites....
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007002569
更新日期:2007-08-01 00:00:00
abstract::The 'Muguga cocktail' live vaccine, delivered by an infection and treatment protocol, has been widely deployed in Eastern, Central and Southern Africa to protect cattle against East Coast fever, caused by Theileria parva. The vaccine contains 3 component stocks (Muguga, Serengeti-transformed and Kiambu 5). In a previo...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007002557
更新日期:2007-08-01 00:00:00
abstract::Serology is an important tool for the diagnosis of alveolar echinococcosis (AE) in humans. In order to improve serodiagnostic performance, we have developed an in vitro-produced Echinococcus mulilocularis metacestode vesicle fluid (EmVF) antigen for application in an immunoblot assay. Immunoblot analysis of EmVF revea...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006002083
更新日期:2007-06-01 00:00:00
abstract::Entomopathogenic nematode infective juveniles are likely to encounter both uninfected and infected insects and host quality depends on the stage of the infection. We hypothesized that nematode response to infected hosts will change over the course of an infection. Here, we tested this hypothesis by focusing on the inf...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001880
更新日期:2007-05-01 00:00:00
abstract::Urinary schistosomiasis is an important source of human morbidity in Msambweni, Kenya, where the intermediate host snail, Bulinus nasutus is found in ponds and water pools. In the past, aquatic habitats in the area have been studied separately; however, recent collections of B. nasutus snails and shells indicated that...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001594
更新日期:2007-05-01 00:00:00
abstract::The phylogenetic relationship of 5 genera, i.e. Diplozoon Nordmann, 1832, Paradiplozoon Achmerov, 1974, Inustiatus Khotenovsky, 1978, Sindiplozoon Khotenovsky, 1981, and Eudiplozoon Khotenovsky, 1985 in the subfamily Diplozoinae Palombi, 1949 (Monogenea, Polyopisthocotylea) was inferred from rDNA ITS-2 region using ne...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001971
更新日期:2007-05-01 00:00:00
abstract::The complete nucleotide sequence of the mitochondrial genome was determined for the fish tapeworm Diphyllobothrium latum. This genome is 13,608 bp in length and encodes 12 protein-coding genes (but lacks the atp8), 22 transfer RNA (tRNA) and 2 ribosomal RNA (rRNA) genes, corresponding to the gene complement found thus...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118200600206X
更新日期:2007-05-01 00:00:00
abstract::Past and more recent research has examined the ultrastructure, metabolism, cell biology, genomics and post-genomics of schistosome schistosomula. These areas are considered and discussed in this review with particular emphasis on (1) the early migration phases through the host, (2) interaction of the host immune respo...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182006001648
更新日期:2007-04-01 00:00:00
abstract::Multiplication of Plasmodium parasites within human erythrocytes is essential to malarial disease. The cell-division cycle of this organism, however, is still poorly understood. In other eukaryotes, various techniques for (apparent) cell-cycle synchronization have been used to shed light on the mechanisms involved in ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001466
更新日期:2007-03-01 00:00:00
abstract::Many zoonotic disease agents are transmitted between hosts by arthropod vectors, including fleas, but few empirical studies of host-vector-microparasite dynamics have investigated the relative importance of hosts and vectors. This study investigates the dynamics of 4 closely related Bartonella species and their flea v...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001624
更新日期:2007-03-01 00:00:00
abstract::Cryptosporidium parvum is composed of multiple subtypes, which appear to be zoonotic or anthroponotic. Therefore, in order to understand the molecular epidemiology of this species and to control the zoonotic transmission, it is essential to identify the isolates at the subtype level. In the present study, 60.2% of 103...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001508
更新日期:2007-03-01 00:00:00
abstract::In this study, the proteome of axenically grown Entamoeba histolytica parasites was explored by two-dimensional gel electrophoresis (2-DE), employing a practical and effective procedure for the solubilization of E. histolytica proteins. Approximately 900 protein species in the pH range between 4 and 7 were detected by...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001442
更新日期:2007-02-01 00:00:00
abstract::cDNA-AFLP (cDNA-Amplified Fragment Length Polymorphism)-based strategy has been used to identify levamisole (LEV) resistance markers in the nematode Haemonchus contortus. Transcript profiles of adult nematodes from two LEV-resistant and two susceptible isolates were compared. Among the 17 280 transcript-derived fragme...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007000030
更新日期:2007-01-01 00:00:00
abstract::We tested whether the prevalence of ticks can be predicted reliably from a simple epidemiological model that takes into account only mean abundance and its variance. We used data on the abundance and distribution of larvae and nymphs of 2 ixodid ticks parasitic on small mammals (Apodemus agrarius, Apodemus flavicollis...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001296
更新日期:2007-01-01 00:00:00
abstract::Ornithodoros moubata ticks were fed on blood infected with Babesia equi. However, the parasites were quickly cleared as evidenced by the disappearance of B. equi-specific ribosomal RNA from the ticks. We hypothesized that if the Babesia parasite can escape midgut-associated barriers a non-vector tick can become infect...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000916
更新日期:2007-01-01 00:00:00
abstract::This review of protozoan and helminth infections in pregnancy focuses on the impact on the immune response in the newborn infant to maternal infection. Studies of protozoan and helminth infections in pregnant women and in their offspring have shown that children exposed to antigens or microorganisms during pregnancy o...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182007000182
更新日期:2007-01-01 00:00:00
abstract::Like in other trypanosomatids D-glucose is a crucial source of energy to Trypanosoma rangeli, a non-pathogenic parasite that in Central and South America infects triatomine vectors and different mammalian species, including humans. In several trypanosome species, D-glucose transporters were already described and clone...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000989
更新日期:2006-12-01 00:00:00